Both comprehension and understanding can be used to talk about someone's ability to understand something. Comprehension usually used with of. The meaning of understanding is a mental grasp :
La Moncloa. 23/09/2025. Pedro Sánchez receives Global Goalkeeper Award
Understanding is a relation between the knower and an object of understanding. He noted bond's apparent lack of. Knowledge about a subject, situation, etc.
Understanding a concept means you get it.
How to use understanding in a sentence. Understanding implies abilities and dispositions with respect to an object. Or about how something works: Your understanding might be that your mother will always drive you to school if you miss the bus.