Understanding implies abilities and dispositions with respect to an object. Understanding a concept means you get it. Understanding is a relation between the knower and an object of understanding.
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Knowledge about a subject, situation, etc. Comprehension usually used with of. The meaning of understanding is a mental grasp :
He noted bond's apparent lack of.
Both comprehension and understanding can be used to talk about someone's ability to understand something. How to use understanding in a sentence. Or about how something works: Your understanding might be that your mother will always drive you to school if you miss the bus.
